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Stress-dependent Daxx-CHIP Interaction Suppresses the p53 Apoptotic Program
Our previous studies have implicated CHIP (carboxyl terminus of Hsp70-interacting protein) as a co-chaperone/ubiquitin ligase whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP and Daxx (death domain-a...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742829/ https://ncbi.nlm.nih.gov/pubmed/19465479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011767 |
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