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Cellular senescence and protein degradation: Breaking down cancer
Autophagy and the ubiquitin–proteasome pathway (UPP) are the major protein degradation systems in eukaryotic cells. Whereas the former mediate a bulk nonspecific degradation, the UPP allows a rapid degradation of specific proteins. Both systems have been shown to play a role in tumorigenesis, and th...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111748/ https://ncbi.nlm.nih.gov/pubmed/24866342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29335 |
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