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Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence
The expression of oncogenic ras in normal human cells quickly induces an aberrant proliferation response that later is curtailed by a cell cycle arrest known as cellular senescence. Here, we show that cells expressing oncogenic ras display an increase in the mitochondrial mass, the mitochondrial DNA...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725737/ https://ncbi.nlm.nih.gov/pubmed/19528227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01868-08 |
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