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Bridging Solutions in Dose Finding Problems

The idea of bridging in dose-finding studies is closely linked to the problem of group heterogeneity. There are some distinctive features in the case of bridging which need to be considered if efficient estimation of the maximum tolerated dose (MTD) is to be accomplished. The case of two distinct po...

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Detalhes bibliográficos
Main Authors: O’Quigley, John, Iasonos, Alexia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111208/
https://ncbi.nlm.nih.gov/pubmed/25071878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2014.906365
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