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Bridging Solutions in Dose Finding Problems

The idea of bridging in dose-finding studies is closely linked to the problem of group heterogeneity. There are some distinctive features in the case of bridging which need to be considered if efficient estimation of the maximum tolerated dose (MTD) is to be accomplished. The case of two distinct po...

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Autors principals: O’Quigley, John, Iasonos, Alexia
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111208/
https://ncbi.nlm.nih.gov/pubmed/25071878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2014.906365
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