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Coherence principles in interval-based dose-finding

This paper studies the notion of coherence in interval-based dose-finding methods. An incoherent decision is either: (i) a recommendation to escalate the dose following an observed dose-limiting toxicity, or (ii) a recommendation to de-escalate the dose following a non-dose-limiting toxicity. In a s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharm Stat
Prif Awduron: Wages, Nolan A., Iasonos, Alexia, O’Quigley, John, Conaway, Mark R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065921/
https://ncbi.nlm.nih.gov/pubmed/31692233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1974
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