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Development of a novel efficient method to construct an adenovirus library displaying random peptides on the fiber knob

Redirection of adenovirus vectors by engineering the capsid-coding region has shown limited success because proper targeting ligands are generally unknown. To overcome this limitation, we constructed an adenovirus library displaying random peptides on the fiber knob, and its screening led to success...

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Hlavní autoři: Yamamoto, Yuki, Goto, Naoko, Miura, Kazuki, Narumi, Kenta, Ohnami, Shumpei, Uchida, Hiroaki, Miura, Yoshiaki, Yamamoto, Masato, Aoki, Kazunori
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110195/
https://ncbi.nlm.nih.gov/pubmed/24380399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4005854
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