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Development of a novel efficient method to construct an adenovirus library displaying random peptides on the fiber knob

Redirection of adenovirus vectors by engineering the capsid-coding region has shown limited success because proper targeting ligands are generally unknown. To overcome this limitation, we constructed an adenovirus library displaying random peptides on the fiber knob, and its screening led to success...

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Detalhes bibliográficos
Main Authors: Yamamoto, Yuki, Goto, Naoko, Miura, Kazuki, Narumi, Kenta, Ohnami, Shumpei, Uchida, Hiroaki, Miura, Yoshiaki, Yamamoto, Masato, Aoki, Kazunori
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110195/
https://ncbi.nlm.nih.gov/pubmed/24380399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4005854
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