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Development of Peritoneal Tumor-Targeting Vector by In Vivo Screening with a Random Peptide-Displaying Adenovirus Library

The targeting of gene transfer at the cell-entry level is one of the most attractive challenges in vector development. However, attempts to redirect adenovirus vectors to alternative receptors by engineering the capsid-coding region have shown limited success, because the proper targeting ligands on...

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Autori principali: Nishimoto, Takeshi, Yamamoto, Yuki, Yoshida, Kimiko, Goto, Naoko, Ohnami, Shumpei, Aoki, Kazunori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447794/
https://ncbi.nlm.nih.gov/pubmed/23029088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045550
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