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Infectivity-selective Oncolytic Adenovirus Developed by High-throughput Screening of Adenovirus-formatted Library

Adenovirus (Ad) is a potent gene-delivery vehicle and has frequently been used for designing oncolytic viruses. However, lack of selectivity on infection has hampered the achievement of sufficient in vivo efficiency. Here, we developed a novel oncolytic virus system, infectivity-selective oncolytic...

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Main Authors: Miura, Yoshiaki, Yamasaki, Satoshi, Davydova, Julia, Brown, Eric, Aoki, Kazunori, Vickers, Selwyn, Yamamoto, Masato
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538312/
https://ncbi.nlm.nih.gov/pubmed/23032977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.205
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