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Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain
Hepatocytes and acinar cells exhibit high-efficiency, fiber-dependent internalization of adenovirus; however, viral capsids have unpredictable immunological effects and are challenging to develop into targeted drug carriers. To exploit this internalization pathway and minimize the use of viral prote...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196066/ https://ncbi.nlm.nih.gov/pubmed/21699930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.06.010 |
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