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Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland

Rapid clearance from the tears presents a formidable obstacle to the delivery of peptide drugs to the eye surface. This impedes therapies for ocular infections, wound healing, and dry-eye disease that affect the vision of millions worldwide. To overcome this challenge, this manuscript explores a nov...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Hsueh, Pang-Yu, Edman, Maria C., Sun, Guoyong, Shi, Pu, Xu, Shi, Lin, Yi-an, Cui, Honggang, Hamm-Alvarez, Sarah F., MacKay, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456098/
https://ncbi.nlm.nih.gov/pubmed/25523518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.12.017
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