Phage Display of Adenovirus Type 5 Fiber Knob as a Tool for Specific Ligand Selection and Validation

Adenovirus (Ad) vectors are most potent for use as gene delivery vehicles to infect human cells in vitro and in vivo with high efficiency. The main limitation in utilization of Ad as a gene transfer vector is the lack of specificity. Genetic modifications of Ad capsid proteins resulting in incorpora...

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Bibliographic Details
Main Authors: Pereboev, Alexander, Pereboeva, Larisa, Curiel, David T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114439/
https://ncbi.nlm.nih.gov/pubmed/11435591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7107-7113.2001
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