Genetic Targeting of an Adenovirus Vector via Replacement of the Fiber Protein with the Phage T4 Fibritin

The utility of adenovirus (Ad) vectors for gene therapy is restricted by their inability to selectively transduce disease-affected tissues. This limitation may be overcome by the derivation of vectors capable of interacting with receptors specifically expressed in the target tissue. Previous attempt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krasnykh, Victor, Belousova, Natalya, Korokhov, Nikolay, Mikheeva, Galina, Curiel, David T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114163/
https://ncbi.nlm.nih.gov/pubmed/11287567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4176-4183.2001
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