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Modification of Adenovirus Capsid with a Designed Protein Ligand Yields a Gene Vector Targeted to a Major Molecular Marker of Cancer

The future of genetic interventions in humans critically depends on the selectivity and efficiency of gene transfer to target tissues. The viral gene vectors explored to date cannot selectively transduce the desired targets. While substantial progress has been made in developing targeting strategies...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Belousova, Natalya, Mikheeva, Galina, Gelovani, Juri, Krasnykh, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224583/
https://ncbi.nlm.nih.gov/pubmed/17989185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01896-07
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