Development of a Targeted Gene Vector Platform Based on Simian Adenovirus Serotype 24

Efforts to develop adenovirus vectors suitable for genetic interventions in humans have identified three major limitations of the most frequently used vector prototype, human adenovirus serotype 5 (Ad5). These limitations—widespread preexisting anti-Ad5 immunity in humans, the high rate of transduct...

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Dades bibliogràfiques
Autors principals: Belousova, Natalya, Mikheeva, Galina, Xiong, Chiyi, Soghomonian, Suren, Young, Daniel, Le Roux, Lucia, Naff, Katherine, Bidaut, Luc, Wei, Wei, Li, Chun, Gelovani, Juri, Krasnykh, Victor
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Gene Delivery
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937776/
https://ncbi.nlm.nih.gov/pubmed/20631120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02425-09
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