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Development of a Targeted Gene Vector Platform Based on Simian Adenovirus Serotype 24
Efforts to develop adenovirus vectors suitable for genetic interventions in humans have identified three major limitations of the most frequently used vector prototype, human adenovirus serotype 5 (Ad5). These limitations—widespread preexisting anti-Ad5 immunity in humans, the high rate of transduct...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937776/ https://ncbi.nlm.nih.gov/pubmed/20631120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02425-09 |
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