Development of a Targeted Gene Vector Platform Based on Simian Adenovirus Serotype 24

Efforts to develop adenovirus vectors suitable for genetic interventions in humans have identified three major limitations of the most frequently used vector prototype, human adenovirus serotype 5 (Ad5). These limitations—widespread preexisting anti-Ad5 immunity in humans, the high rate of transduct...

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Detalhes bibliográficos
Main Authors: Belousova, Natalya, Mikheeva, Galina, Xiong, Chiyi, Soghomonian, Suren, Young, Daniel, Le Roux, Lucia, Naff, Katherine, Bidaut, Luc, Wei, Wei, Li, Chun, Gelovani, Juri, Krasnykh, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937776/
https://ncbi.nlm.nih.gov/pubmed/20631120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02425-09
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