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Modification of Adenovirus Capsid with a Designed Protein Ligand Yields a Gene Vector Targeted to a Major Molecular Marker of Cancer

The future of genetic interventions in humans critically depends on the selectivity and efficiency of gene transfer to target tissues. The viral gene vectors explored to date cannot selectively transduce the desired targets. While substantial progress has been made in developing targeting strategies...

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Autori principali: Belousova, Natalya, Mikheeva, Galina, Gelovani, Juri, Krasnykh, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224583/
https://ncbi.nlm.nih.gov/pubmed/17989185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01896-07
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