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Genetic Targeting of an Adenovirus Vector via Replacement of the Fiber Protein with the Phage T4 Fibritin

The utility of adenovirus (Ad) vectors for gene therapy is restricted by their inability to selectively transduce disease-affected tissues. This limitation may be overcome by the derivation of vectors capable of interacting with receptors specifically expressed in the target tissue. Previous attempt...

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Autors principals: Krasnykh, Victor, Belousova, Natalya, Korokhov, Nikolay, Mikheeva, Galina, Curiel, David T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114163/
https://ncbi.nlm.nih.gov/pubmed/11287567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4176-4183.2001
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