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Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors

The leishmaniases are a spectrum of global diseases of poverty associated with immune dysfunction and are the cause of high morbidity. Despite the long history of these diseases, no effective vaccine is available and the currently used drugs are variously compromised by moderate efficacy, complex si...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brannigan, James A., Roberts, Shirley M., Bell, Andrew S., Hutton, Jennie A., Hodgkinson, Michael R., Tate, Edward W., Leatherbarrow, Robin J., Smith, Deborah F., Wilkinson, Anthony J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107925/
https://ncbi.nlm.nih.gov/pubmed/25075346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252514013001
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