Cargando...
Peptidomimetic inhibitors of N-myristoyltransferase from human malaria and leishmaniasis parasites
N-Myristoyltransferase (NMT) has been shown to be essential in Leishmania and subsequently validated as a drug target in Plasmodium. Herein, we discuss the use of antifungal NMT inhibitors as a basis for inhibitor development resulting in the first sub-micromolar peptidomimetic inhibitors of Plasmod...
Gardado en:
| Publicado en: | Org Biomol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2014
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224572/ https://ncbi.nlm.nih.gov/pubmed/25230674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01669f |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|