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Peptidomimetic inhibitors of N-myristoyltransferase from human malaria and leishmaniasis parasites
N-Myristoyltransferase (NMT) has been shown to be essential in Leishmania and subsequently validated as a drug target in Plasmodium. Herein, we discuss the use of antifungal NMT inhibitors as a basis for inhibitor development resulting in the first sub-micromolar peptidomimetic inhibitors of Plasmod...
Gorde:
| Argitaratua izan da: | Org Biomol Chem |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Royal Society of Chemistry
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224572/ https://ncbi.nlm.nih.gov/pubmed/25230674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01669f |
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