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Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase
The parasite Plasmodium vivax is the most widely distributed cause of recurring malaria. N-Myristoyltransferase (NMT), an enzyme that catalyses the covalent attachment of myristate to the N-terminal glycine of substrate proteins, has been described as a potential target for the treatment of this dis...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463734/ https://ncbi.nlm.nih.gov/pubmed/28626547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00531d |
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