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Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase
N-Myristoyltransferase (NMT) represents an attractive drug target in parasitic infections such as malaria due to its genetic essentiality and amenability to inhibition by drug-like small molecules. Scaffold simplification from previously reported inhibitors containing bicyclic cores identified pheny...
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| Pubblicato in: | Medchemcomm |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757856/ https://ncbi.nlm.nih.gov/pubmed/26962430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5md00242g |
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