Carregant...

Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes

[Image: see text] The leishmaniases, caused by Leishmania species of protozoan parasites, are neglected tropical diseases with millions of cases worldwide. Current therapeutic approaches are limited by toxicity, resistance, and cost. N-Myristoyltransferase (NMT), an enzyme ubiquitous and essential i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Med Chem
Autors principals: Bell, Andrew S., Yu, Zhiyong, Hutton, Jennie A., Wright, Megan H., Brannigan, James A., Paape, Daniel, Roberts, Shirley M., Sutherell, Charlotte L., Ritzefeld, Markus, Wilkinson, Anthony J., Smith, Deborah F., Leatherbarrow, Robin J., Tate, Edward W.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383931/
https://ncbi.nlm.nih.gov/pubmed/32575985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00570
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!