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Environmental contaminants perturb fragile protein assemblies and inhibit normal protein function
The molecular mechanisms whereby small molecules that contaminate our environment cause physiological effects are largely unknown, in terms of both targets and mechanisms. The essential human enzyme porphobilinogen synthase (HsPBGS, a.k.a. 5-aminolevulinate dehydratase, ALAD) functions in heme biosy...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102012/ https://ncbi.nlm.nih.gov/pubmed/25045409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212796811307020011 |
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