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Environmental contaminants perturb fragile protein assemblies and inhibit normal protein function

The molecular mechanisms whereby small molecules that contaminate our environment cause physiological effects are largely unknown, in terms of both targets and mechanisms. The essential human enzyme porphobilinogen synthase (HsPBGS, a.k.a. 5-aminolevulinate dehydratase, ALAD) functions in heme biosy...

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Autors principals: Lawrence, Sarah H., Selwood, Trevor, Jaffe, Eileen K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102012/
https://ncbi.nlm.nih.gov/pubmed/25045409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212796811307020011
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