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Environmental contaminants perturb fragile protein assemblies and inhibit normal protein function

The molecular mechanisms whereby small molecules that contaminate our environment cause physiological effects are largely unknown, in terms of both targets and mechanisms. The essential human enzyme porphobilinogen synthase (HsPBGS, a.k.a. 5-aminolevulinate dehydratase, ALAD) functions in heme biosy...

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Bibliografiske detaljer
Main Authors: Lawrence, Sarah H., Selwood, Trevor, Jaffe, Eileen K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102012/
https://ncbi.nlm.nih.gov/pubmed/25045409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212796811307020011
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