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Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis

In many mammalian cell types, integrin-mediated cell-matrix adhesion is required for the G1–S transition of the cell cycle. As cells approach mitosis, a dramatic remodeling of their cytoskeleton accompanies dynamic changes in matrix adhesion, suggesting a mechanistic link. However, the role of integ...

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Detalhes bibliográficos
Main Authors: Reverte, Carlos G., Benware, Angela, Jones, Christopher W., LaFlamme, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064255/
https://ncbi.nlm.nih.gov/pubmed/16908668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200603069
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