Integrins Regulate Microtubule Nucleating Activity of Centrosome through Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase/Extracellular Signal-regulated Kinase (MEK/ERK) Signaling

Microtubule nucleation is an essential step in the formation of the microtubule cytoskeleton. We recently showed that androgen and Src promote microtubule nucleation and γ-tubulin accumulation at the centrosome. Here, we explore the mechanisms by which androgen and Src regulate these processes and a...

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Bibliographic Details
Main Authors: Colello, Diane, Mathew, Shomita, Ward, Rachel, Pumiglia, Kevin, LaFlamme, Susan E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268412/
https://ncbi.nlm.nih.gov/pubmed/22117069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254128
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