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Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal–regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment

Common lymphoid progenitors (CLPs) are lymphoid-lineage-committed progenitor cells. However, they maintain a latent myeloid differentiation potential that can be initiated by stimulation with interleukin-2 (IL-2) via ectopically expressed IL-2 receptors. Although CLPs express IL-7 receptors, which s...

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Bibliografiske detaljer
Main Authors: Hsu, Chia-Lin, Kikuchi, Kazu, Kondo, Motonari
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975832/
https://ncbi.nlm.nih.gov/pubmed/17536016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-02-071761
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