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Environmental contaminants perturb fragile protein assemblies and inhibit normal protein function

The molecular mechanisms whereby small molecules that contaminate our environment cause physiological effects are largely unknown, in terms of both targets and mechanisms. The essential human enzyme porphobilinogen synthase (HsPBGS, a.k.a. 5-aminolevulinate dehydratase, ALAD) functions in heme biosy...

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Bibliografske podrobnosti
Main Authors: Lawrence, Sarah H., Selwood, Trevor, Jaffe, Eileen K.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102012/
https://ncbi.nlm.nih.gov/pubmed/25045409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2212796811307020011
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