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Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2
Follicle-stimulating hormone (FSH) is an essential regulator of gonadal function and fertility. Loss-of-function mutations in the FSHB/Fshb gene cause hypogonadotropic hypogonadism in humans and mice. Both gonadotropin-releasing hormone (GnRH) and activins, members of the transforming growth factor...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101660/ https://ncbi.nlm.nih.gov/pubmed/24739304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-249532 |
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