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Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2

Follicle-stimulating hormone (FSH) is an essential regulator of gonadal function and fertility. Loss-of-function mutations in the FSHB/Fshb gene cause hypogonadotropic hypogonadism in humans and mice. Both gonadotropin-releasing hormone (GnRH) and activins, members of the transforming growth factor...

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Detalhes bibliográficos
Main Authors: Fortin, Jérôme, Boehm, Ulrich, Deng, Chu-Xia, Treier, Mathias, Bernard, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101660/
https://ncbi.nlm.nih.gov/pubmed/24739304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-249532
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