Activator Protein-1 and Smad Proteins Synergistically Regulate Human Follicle-Stimulating Hormone β-Promoter Activity

GnRH1 stimulates the synthesis and secretion of FSH and LH from the anterior pituitary gland. The molecular mechanisms through which GnRH1 produces these effects in humans have not been determined. Here, we examined transcriptional regulation of the human FSHβ (FSHB) subunit using reporter assays in...

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Autori principali: Wang, Ying, Fortin, Jérôme, Lamba, Pankaj, Bonomi, Marco, Persani, Luca, Roberson, Mark S., Bernard, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584589/
https://ncbi.nlm.nih.gov/pubmed/18653705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0220
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