Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells

The activin/inhibin system regulates follicle-stimulating hormone (FSH) synthesis and release by pituitary gonadotrope cells in mammals. In vitro cell line data suggest that activins stimulate FSH β-subunit (Fshb) transcription via complexes containing the receptor-regulated SMAD proteins SMAD2 and...

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Bibliografiske detaljer
Main Authors: Fortin, Jérôme, Boehm, Ulrich, Weinstein, Michael B., Graff, Jonathan M., Bernard, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2014
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929678/
https://ncbi.nlm.nih.gov/pubmed/24308975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-237818
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