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SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cells in Vivo

Pituitary follicle-stimulating hormone (FSH) is an essential regulator of fertility in females and of quantitatively normal spermatogenesis in males. Pituitary-derived activins are thought to act as major stimulators of FSH synthesis by gonadotrope cells. In vitro, activins signal via SMAD3, SMAD4,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Yining, Schang, Gauthier, Boehm, Ulrich, Deng, Chu-Xia, Graff, Jonathan, Bernard, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313102/
https://ncbi.nlm.nih.gov/pubmed/27994055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759167
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