Conditional Deletion of FOXL2 and SMAD4 in Gonadotropes of Adult Mice Causes Isolated FSH Deficiency

The glycoprotein FSH, a product of pituitary gonadotrope cells, regulates ovarian follicle development in females and spermatogenesis in males. FSH is a heterodimer of the common α gonadotropin subunit and the hormone-specific FSHβ subunit (a product of the Fshb gene). Using a conditional knockout a...

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Publicat a:Endocrinology
Autors principals: Li, Yining, Schang, Gauthier, Wang, Ying, Zhou, Xiang, Levasseur, Adrien, Boyer, Alexandre, Deng, Chu-Xia, Treier, Mathias, Boehm, Ulrich, Boerboom, Derek, Bernard, Daniel J
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692885/
https://ncbi.nlm.nih.gov/pubmed/29800110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00100
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