Human Follicle-Stimulating Hormone ß Subunit Expression Depends on FOXL2 and SMAD4

Follicle-stimulating hormone (FSH), an essential regulator of mammalian fertility, is synthesized by pituitary gonadotrope cells in response to activins. In mice, activins signal via SMAD3, SMAD4, and FOXL2 to regulate transcription of the FSHβ subunit (Fshb) gene. Gonadotrope-specific deletion of F...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Ongaro, Luisina, Schang, Gauthier, Zhou, Ziyue, Kumar, T Rajendra, Treier, Mathias, Deng, Chu-Xia, Boehm, Ulrich, Bernard, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182064/
https://ncbi.nlm.nih.gov/pubmed/32191302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa045
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