Human Follicle-Stimulating Hormone ß Subunit Expression Depends on FOXL2 and SMAD4

Follicle-stimulating hormone (FSH), an essential regulator of mammalian fertility, is synthesized by pituitary gonadotrope cells in response to activins. In mice, activins signal via SMAD3, SMAD4, and FOXL2 to regulate transcription of the FSHβ subunit (Fshb) gene. Gonadotrope-specific deletion of F...

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Foilsithe in:Endocrinology
Main Authors: Ongaro, Luisina, Schang, Gauthier, Zhou, Ziyue, Kumar, T Rajendra, Treier, Mathias, Deng, Chu-Xia, Boehm, Ulrich, Bernard, Daniel J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182064/
https://ncbi.nlm.nih.gov/pubmed/32191302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa045
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