Human Follicle-Stimulating Hormone ß Subunit Expression Depends on FOXL2 and SMAD4

Follicle-stimulating hormone (FSH), an essential regulator of mammalian fertility, is synthesized by pituitary gonadotrope cells in response to activins. In mice, activins signal via SMAD3, SMAD4, and FOXL2 to regulate transcription of the FSHβ subunit (Fshb) gene. Gonadotrope-specific deletion of F...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Ongaro, Luisina, Schang, Gauthier, Zhou, Ziyue, Kumar, T Rajendra, Treier, Mathias, Deng, Chu-Xia, Boehm, Ulrich, Bernard, Daniel J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182064/
https://ncbi.nlm.nih.gov/pubmed/32191302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa045
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