Human Follicle-Stimulating Hormone ß Subunit Expression Depends on FOXL2 and SMAD4

Follicle-stimulating hormone (FSH), an essential regulator of mammalian fertility, is synthesized by pituitary gonadotrope cells in response to activins. In mice, activins signal via SMAD3, SMAD4, and FOXL2 to regulate transcription of the FSHβ subunit (Fshb) gene. Gonadotrope-specific deletion of F...

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Pubblicato in:Endocrinology
Autori principali: Ongaro, Luisina, Schang, Gauthier, Zhou, Ziyue, Kumar, T Rajendra, Treier, Mathias, Deng, Chu-Xia, Boehm, Ulrich, Bernard, Daniel J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182064/
https://ncbi.nlm.nih.gov/pubmed/32191302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa045
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