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Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer

The neddylation pathway has been recognized as an attractive anticancer target in several malignancies, and its selective inhibitor, MLN4924, has recently advanced to clinical development. However, the anticancer effect of this compound against prostate cancer has not been well investigated. In this...

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Detalhes bibliográficos
Main Authors: Wang, Xiaofang, Li, Lihui, Liang, Yupei, Li, Chunjie, Zhao, Hu, Ye, Dingwei, Sun, Menghong, Jeong, Lak Shin, Feng, Yan, Fu, Shen, Jia, Lijun, Guo, Xiaomao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100379/
https://ncbi.nlm.nih.gov/pubmed/25093192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/974309
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