Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells

Salvage radiotherapy (SRT) is the first-line treatment for prostate cancer patients with biochemical recurrence following radical prostatectomy, and new specific radiosensitizers are in urgent need to enhance SRT effect. MLN4924 (also known as Pevonedistat), a specific inhibitor of NEDD8-activating...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wang, Xiaofang, Zhang, Wenjuan, Yan, Zi, Liang, Yupei, Li, Lihui, Yu, Xiaoli, Feng, Yan, Fu, Shen, Zhang, Yanmei, Zhao, Hu, Yu, Jinha, Jeong, Lak Shin, Guo, Xiaomao, Jia, Lijun
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122397/
https://ncbi.nlm.nih.gov/pubmed/27224919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9526
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