Suppression of glioblastoma by targeting the overactivated protein neddylation pathway

BACKGROUND: The neddylation pathway has been recently identified as an attractive anticancer target, and MLN4924, a specific NEDD8-activating enzyme inhibitor, has been developed as a first-in-class anticancer agent. However, neither the status of the neddylation pathway in glioblastoma (GBM) nor th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Hua, Wei, Li, Chunjie, Yang, Zixiao, Li, Lihui, Jiang, Yanan, Yu, Guangyang, Zhu, Wei, Liu, Zhengyan, Duan, Shengzhong, Chu, Yiwei, Yang, Meng, Zhang, Yanmei, Mao, Ying, Jia, Lijun
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578582/
https://ncbi.nlm.nih.gov/pubmed/25904638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov066
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