Inhibition of Neddylation Modification Sensitizes Pancreatic Cancer Cells to Gemcitabine

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the USA with a 5-year survival rate less than 3% to 5%. Gemcitabine remains as a standard care for PDAC patients. Although protein neddylation is abnormally activated in many human cancers, whether neddylation dys...

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Publicat a:Neoplasia
Autors principals: Li, Hua, Zhou, Weihua, Li, Lihui, Wu, Jianfu, Liu, Xiaoli, Zhao, Lili, Jia, Lijun, Sun, Yi
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2017
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440286/
https://ncbi.nlm.nih.gov/pubmed/28535453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.04.003
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