Validation of an Oligonucleotide Ligation Assay for Quantification of Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by Use of Massively Parallel Sequencing

Global HIV treatment programs need sensitive and affordable tests to monitor HIV drug resistance. We compared mutant detection by the oligonucleotide ligation assay (OLA), an economical and simple test, to massively parallel sequencing. Nonnucleoside reverse transcriptase inhibitor (K103N, V106M, Y1...

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Main Authors: Beck, Ingrid A., Deng, Wenjie, Payant, Rachel, Hall, Robert, Bumgarner, Roger E., Mullins, James I., Frenkel, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Virology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097683/
https://ncbi.nlm.nih.gov/pubmed/24740080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00306-14
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