Rapid and Sensitive Oligonucleotide Ligation Assay for Detection of Mutations in Human Immunodeficiency Virus Type 1 Associated with High-Level Resistance to Protease Inhibitors

A sensitive, specific, and high-throughput oligonucleotide ligation assay (OLA) for the detection of genotypic human immunodeficiency virus type 1 (HIV-1) resistance to Food and Drug Administration-approved protease inhibitors was developed and evaluated. This ligation-based assay uses differentiall...

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Detalhes bibliográficos
Main Authors: Beck, Ingrid A., Mahalanabis, Madhumita, Pepper, Gregory, Wright, Amy, Hamilton, Shannon, Langston, Erika, Frenkel, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140364/
https://ncbi.nlm.nih.gov/pubmed/11923366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.4.1413-1419.2002
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