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Validation of an Oligonucleotide Ligation Assay for Quantification of Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by Use of Massively Parallel Sequencing

Global HIV treatment programs need sensitive and affordable tests to monitor HIV drug resistance. We compared mutant detection by the oligonucleotide ligation assay (OLA), an economical and simple test, to massively parallel sequencing. Nonnucleoside reverse transcriptase inhibitor (K103N, V106M, Y1...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Beck, Ingrid A., Deng, Wenjie, Payant, Rachel, Hall, Robert, Bumgarner, Roger E., Mullins, James I., Frenkel, Lisa M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097683/
https://ncbi.nlm.nih.gov/pubmed/24740080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00306-14
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