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Development and validation of an oligonucleotide ligation assay to detect lamivudine resistance in hepatitis B virus
Treatment of chronic hepatitis B virus (HBV) infection with lamivudine-monotherapy rapidly selects mutant variants in a high proportion of individuals. Monitoring lamivudine resistance by consensus sequencing is costly and insensitive for detection of minority variants. An oligonucleotide ligation a...
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| Publicado no: | J Virol Methods |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5074383/ https://ncbi.nlm.nih.gov/pubmed/27025356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2016.03.014 |
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