Development and validation of an oligonucleotide ligation assay to detect lamivudine resistance in hepatitis B virus

Treatment of chronic hepatitis B virus (HBV) infection with lamivudine-monotherapy rapidly selects mutant variants in a high proportion of individuals. Monitoring lamivudine resistance by consensus sequencing is costly and insensitive for detection of minority variants. An oligonucleotide ligation a...

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Bibliografiset tiedot
Julkaisussa:J Virol Methods
Päätekijät: Beck, Ingrid A., Payant, Rachel, Ngo-Giang-Huong, Nicole, Khamduang, Woottichai, Laomanit, Laddawan, Jourdain, Gonzague, Frenkel, Lisa M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074383/
https://ncbi.nlm.nih.gov/pubmed/27025356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2016.03.014
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