Validation of an Oligonucleotide Ligation Assay for Quantification of Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by Use of Massively Parallel Sequencing

Global HIV treatment programs need sensitive and affordable tests to monitor HIV drug resistance. We compared mutant detection by the oligonucleotide ligation assay (OLA), an economical and simple test, to massively parallel sequencing. Nonnucleoside reverse transcriptase inhibitor (K103N, V106M, Y1...

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Détails bibliographiques
Auteurs principaux: Beck, Ingrid A., Deng, Wenjie, Payant, Rachel, Hall, Robert, Bumgarner, Roger E., Mullins, James I., Frenkel, Lisa M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Virology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097683/
https://ncbi.nlm.nih.gov/pubmed/24740080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00306-14
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