Oligonucleotide Ligation Assay for Detecting Mutations in the Human Immunodeficiency Virus Type 1 pol Gene That Are Associated with Resistance to Zidovudine, Didanosine, and Lamivudine

This report describes the detection of mutations in the pol gene of human immunodeficiency virus type 1 associated with resistance to zidovudine, didanosine, and lamivudine by genotyping by an oligonucleotide ligation assay specific codons in the pol gene amplified by PCR. Our studies demonstrate th...

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Autores principales: Edelstein, Reva E., Nickerson, Deborah A., Tobe, Vincent O., Manns-Arcuino, Laura A., Frenkel, Lisa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Virology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC104580/
https://ncbi.nlm.nih.gov/pubmed/9466779
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