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Oligonucleotide Ligation Assay for Detecting Mutations in the Human Immunodeficiency Virus Type 1 pol Gene That Are Associated with Resistance to Zidovudine, Didanosine, and Lamivudine

This report describes the detection of mutations in the pol gene of human immunodeficiency virus type 1 associated with resistance to zidovudine, didanosine, and lamivudine by genotyping by an oligonucleotide ligation assay specific codons in the pol gene amplified by PCR. Our studies demonstrate th...

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Udgivet i:J Clin Microbiol
Principais autores: Edelstein, Reva E., Nickerson, Deborah A., Tobe, Vincent O., Manns-Arcuino, Laura A., Frenkel, Lisa M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Virology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9466779/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.36.2.569-572.1998
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